Kidney cancer are present on either side of the backbone and their main function is to remove the waste and make urine. Kidney cancer occurs when there is a growth of tumor on one or both the kidneys.
The signs of kidney cancer are such as –
- Blood in the urine
- Presence of a lump in the abdomen
- Pain in the sides
- Loss of appetite
- Weight loss
Risk factors for Kidney Cancer are –
- Smoking- it not only increases the probability of lung cancer but it also increases the chances of kidney cancer.
- Being overweight also increases the chances.
- High blood pressure is not good for kidney cancer.
- Having kidney cancer in the family also increases the chances.
- Long term use of phenacetin, a pain relief drug.
- Men are more prone to kidney cancer then women.
- Exposure to asbestos or cadmium.
- Genetic disease such as Hippel Lindau disease and others.
- Undergoing long term dialysis increases the risk of getting the cancer of kidneys.
- Immunosuppressant medications taken during kidney transplant can increase the risk of cancer.
Types of kidney Cancer are such as –
- Renal cell carcinoma – it is the most common form of kidney cancer and starts in the lining of the renal tubules. This cancer can easily spread to the other parts of the body mostly the brain and the lungs.
- Clear cell renal cell carcinoma – also called the conventional renal cell carcinoma and is about 80% of all renal cell carcinoma cases.
- Some of the rare kidney cancers are – papillary renal cell carcinoma and translocation renal cell carcinoma.
Diagnostic tests for kidney Cancer –
- Imaging tests such as ultrasound which uses high energy sound waves to form the picture of the kidney.
- Magnetic resonance imaging – uses radio waves to form the image.
- CT scan – detailed picture of the pelvis is obtained.
- Urinalysis – check for the presence of glucose, proteins and blood cells in the urine signifying faulty kidneys.
- Biopsy – cells are examined and the cells are obtained by inserting a thin needle into the tumor.
Treatment of Kidney Cancer –
- Surgery – removal of the complete kidney or the part of kidney having tumor.
- Radiation therapy – use of X-rays to shrink or eradicate the cancerous cells.
- Chemotherapy – use of medications which stop the growth of the cancer cells or by stopping the division of the cancer cells.
- Immunotherapy – use of medications which affect the immune system and they attack the cancer cells
- Targeted therapy – use of medications which identify and attack the specific cancer cells and factors. For example – monoclonal antibodies and kinase inhibitors.
Sutent 50mg is also known by the generic name Sunitinib and it is useful for treating kidney cancer and gastrointestinal cancer. This tablet blocks the activity of VEGFR which are used by the cancer cells to grow and nourish. Sutent tablet is available as 50mg, 25mg and 12.5 mg tablets. The price of Sutent is high however it can be purchased from Magicine Pharma at a low price as they are providing various discounts with their medicines. Some of the side effects of Sutent are – diarrhea, constipation, discoloration of hair, rash, fatigue and fever and dry skin.
Inlyta 5mg also known by the generic name Axitinib and it treats advanced renal cell carcinoma. Inlyta is the kinase inhibitor which stops the cell proliferation of the cancer cells. Some of the side effects of Inlyta are such as – cough, diarrhea, weight loss, nausea, loss of appetite, changes in the voice, tingling in the skin of hands and feet, sore mouth, heartburn, and headache. The price of Inlyta tablet is high however you can purchase it from Magicine Pharma to get these at 15% off.